FDA approves intravenous version of Tesaro drug for chemotherapy nausea

The intravenous version of the already-approved drug, Varubi, will be used in combination with other agents to prevent delayed nausea and vomiting associated with some forms of chemotherapy, the company said in a statement. The oral version of Varubi was approved by the FDA in 2015.

The intravenous formulation will be launched in November and cost less than the oral drug, Tesaro's chief executive, Lonnie Moulder, told Reuters in an interview. It will have a list price of $295 per ready-to-use vial, compared to $561.80 for the oral drug, Moulder said.

Chemotherapy-induced nausea and vomiting is considered one of the most acute side effects of cancer therapy and affects up to 80 percent of patients, according to the National Institute of Health.

Varubi works by blocking the activation of neurokinin (NK)-1 receptors in the nervous system that play an important role in nausea and vomiting.

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