FDA Warns That Fluoroquinolone Antibiotics Can Cause Permanent Nerve Damage

Unfortunately, this warning is too late for patients already suffering from permanent side effects caused by this dangerous category of antibiotics.

Sold under the brand names Levaquin, Cipro and Avelox, fluoroquinolone antibiotics are taken by an estimated 26 million Americans each year. The new FDA directive will force manufacturers to provide a stronger warning regarding their use.  Keep in mind, when the FDA issues a warning, you know the drug is really toxic and dangerous.

FDA warns: Fluoroquinolone antibiotics offer ‘serious side effects’ which outweigh the benefits

In May, the FDA announced it was requiring manufacturers of these drugs to include a tougher black box warning. Following an advisory committee meeting held in November, the FDA issued the new requirement, warning that the agency now believes the serious side effects associated with fluoroquinolone antibacterial drugs outweigh the benefits for many patients.

That’s strong language coming from an agency that often seems to turn a blind eye toward evidence suggesting serious health risks associated with any pharmaceutical substance.  The agency had previously added boxed warnings for fluoroquinolones back in 2008 – specifically for tendon rupture and tendinitis. A second warning came again in 2013 for peripheral neuropathy, a type of permanent nerve damage.

Adverse reactions to fluoroquinolones can lead to permanent damage

While the list of dangerous side effects of Levaquin and other fluoroquinolones is long and varied, these antibiotics are known to be a primary cause of peripheral neuropathy. This condition can lead to nerve damage, with symptoms such as muscle tingling, numbness and muscle weakness. In advanced cases, the condition causes persistent burning pain, muscle wasting, paralysis, respiratory issues, and organ dysfunction – which can lead to organ failure.

But that isn’t the entire story. A number of additional adverse reactions to the drugs have been identified over the years, including diarrhea, nausea, migraines, abnormal liver function, vomiting, skin rash, abdominal pain, and pain in the extremities. Fluoroquinolones have also been linked to cardiovascular problems, including palpitation, ventricular ectopy, atrial flutter, hypertension, angina, cerebral thrombosis, myocardial infarction, and cardiopulmonary arrest.

n addition to an alarming number of problems with the central nervous system, these antibiotics are known to cause gastrointestinal, musculoskeletal, renal and respiratory problems, among others.  And, while many of the fluoroquinolones have been removed from the marketplace because of their substantial side effects, Levaquin, Cipro and Avelox remain in use.

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