| S | Saline Flush | Ensures patency of the line and clears the line of residual medication | 
| A | Administer | Administration of the medication or connection of the infusion | 
| S | Saline Flush | Ensures patency of the line and clears the line of residual medication | 
| H | Heparin (If the device requires heparin for patency) | To minimize the potential of a blood clot forming inside the central line lumen |