Main intracellular fluid (ICF) cation
Affects a cell’s electrical status when permeating cell membranes
Regulates cell excitability
Balances ICF osmolality and ICF osmotic pressure
A leading ICF cation
Contributes to enzymatic and metabolic processes (i.e. protein synthesis)
Modifies neural communication, heart function and skeletal muscle response
Main ICF anion
Acts as a hydrogen buffer and acid/base balance
Formation of red blood cells
Supports energy storage and carbohydrate, protein, and fat metabolism
Main extracellular fluid (ECF) cation
Activates nerve and muscle cells
Helps maintain acid-base balance
Helps govern normal osmolality
Maintains fluid balance in the blood
Main ECF anion
Helps maintain normal ECF osmolality
Affects body pH
Plays a vital role in maintaining acid-base balance; combines with hydrogen ions to produce hydrochloric acid
A major cation in teeth and bones; found in fairly equal concentrations in ICF and ECF
Helps cells maintain their shape and adhere to one another
Acts as an enzyme activator within cells
Aids blood coagulation
Affects cell membrane permeability and firing level
Important role in muscle contraction
Inhibitory affect on neurons
Present in ECF
Primary function is regulating acid-base balance
Affected by food, medications, kidney and lung function