Nurse caring for oncology patient

Overview of Antineoplastic Therapy

Since cancer is so prevalent, nurses in all healthcare settings interact with patients with a current cancer diagnosis, as well as cancer survivals. As such, understanding the basic principles behind cancer and antineoplastic therapy is important for nurses in all clinical settings. The landscape is constantly changing in the field of oncology and antineoplastic therapy. Not only are new medications within existing classifications and new medication combinations emerging, but whole new classes of medications are being developed at an exponentially advancing rate. This course provides an overview of antineoplastic therapy in the current landscape.

State Boards of Nursing have varying positions on the role of the LPN/LVN in the administration of infusion therapy, including the administration of antineoplastic agents. A link to each state board of nursing is listed here. Competency requirements are obtained and maintained through the nurse’s employer, facility or institution.

Curriculum

Chapter 1: Introduction

  • Definitions
  • Goals of Antineoplastic Therapy
Chapter 2: Introduction to Chemotherapy
  • Cell Cycle and Chemotherapy
  • Antineoplastic Approaches
    • Neoadjuvant Therapy
    • Consolidation Therapy
    • Primary Therapy
    • Adjuvant Therapy
    • Combination Therapy
    • Maintenance Therapy
Chapter 3: Chemotherapy Classifications
  • Mechanisms of Action
    • Alkylating And Alkylating-Like Agents
    • Antimetabolites
    • Antitumor Antibiotics
    • Mitotic Inhibitors
    • Topoisomerase Inhibitors
  • Hormone Therapy
  • Miscellaneous
Chapter 4: Introduction to Immunotherapy
Chapter 5: Immunotherapy Classifications
  • Monoclonal Antibodies
    • Naked Monoclonal Antibodies
    • Conjugated Monoclonal Antibodies
    • Bispecific Monoclonal Antibodies
  • Immune Checkpoint Inhibitors
  • Cytokines
    • Interferons
    • Interleukins
  • Oncolytic Virus Therapy
  • Cancer Vaccines
  • Antigen Vaccines
  • CAR T-cell Therapy
  • Tumor-infiltrating Lymphocytes
  • Immunomodulating Agents
  • Cryoimmunology
Chapter 6: Targeted Therapy
  • Receptor Tyrosine Kinase Inhibitors
  • KRAS Inhibitors
  • Other Signal Inhibitors
Chapter 7: Adverse Effects
  • Myelosuppression
    • Anemia
    • Neutropenia
    • Thrombocytopenia
  • Gastrointestinal
    • Anorexia
    • Constipation
    • Diarrhea
    • Mucositis
    • Nausea/Vomiting
    • Xerostomia
    • Pharmacologic Interventions
  • Integumentary
    • Alopecia
    • Radiation Recall
    • Hand-Foot Syndrome
    • Immunotherapy Skin Reactions
  • Cardiovascular
  • Respiratory
  • Renal/Urinary
  • Neurologic
  • Endocrine
  • Reproductive
Chapter 8: Cryoprotective Agents
  • Dexrazoxane
  • Folic Acid and Vitamin B12
  • Folinic Acid
  • Mesna
  • MuGard
  • Palifermin
  • Scalp Cooling
  • Trilaciclib
Chapter 9: Safe Handling
  • Closed System Transfer Devices
  • Preparation
  • Administration
  • Disposal
  • Bodily Discharges
Chapter 10: Administration
  • Pre-administration Activities
  • Routes of Administration
Chapter 11: Psychological Considerations

Chapter 12: References

Price: $54.00

Contact Hours: 4.5

Nurse caring for oncology patient

Course Author

Author photo for Pamela Clark

Pamela Clark

Pamela Clark, CRNI, is an infusion nurse with the Houston Methodist Sugar Land Hospital. She has more than 35 years of experience in infusion therapy and infusion education with both licensed nurses and patients. Her experience spans multiple infusion settings including: acute care, long-term care, home infusion, and ambulatory infusion care. She also has experience in oncology and oncology research.

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